With the growth of open science and open access movement, Ecosystem of knowledge evolve and is living a kind of revolution. New actors emerge with the rise of open data and open knowledge in general. New business models has to be found based on service and no more on production. Which are this new actors and initiatives? How do they insert and deal with the traditional models? Which are the new use and practice that we could we see happening with open science? We will try to bring answer to this questions with our different speakers?