This year’s OAWeek preparations kick off with a challenge to researchers from Dr. Philip E. Bourne, Professor of Pharmacy and Pharmaceutical Sciences at the University of California San Diego and Founding Editor-in-Chief of PLoS Computational Biology. In a video posted to the OA Week Web site, Bourne calls upon scholars to think beyond free and ready access to the literature – made possible by Open Access – and consider how technology may be deployed to advance research, to truly mine the increasing amount of available literature.